Aurora-B knockdown inhibits osteosarcoma metastasis by inducing autophagy via the mTOR/ULK1 pathway
Abstract Background Autophagy plays an essential role in metastasis of malignancies.Although our studies showed that Aurora-B facilitate pulmonary metastasis in OS, the mechanism of Aurora-B kinase on autophagy and metastasis in OS has not been explored.Methods Clinical-pathological parameters and follow-up information was collected in OS patients.